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| tolerogenic therapy ： ウィキペディア英語版 |
tolerogenic therapy
Tolerogenic therapy aims to induce immune tolerance where there is pathological or undesirable activation of the normal immune response. This can occur, for example, when an allogeneic transplantation patient develops an immune reaction to donor antigens, or when the body responds inappropriately to self antigens implicated in autoimmune diseases.
Research using animal models in transplantation and autoimmune diseases has led to early-phase human trials of toleragenic therapy for autoimmune conditions like Type 1 Diabetes.
==Dendritic cells in tolerogenic therapy==
Tolerogenic therapies employ the inbuilt tolerance mechanisms of a class of immune cells called dendritic cells. Dendritic cells are divided into two main subsets:
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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